What is PRP?
Platelet Rich Plasma (PRP) is an innovative and promising approach in tissue regeneration1. PRP is defined as an autologous concentrated preparation of platelets and their associated growth factors in a small volume of plasma1. PRP allows patients to take advantage of the body's natural capacity for healing at a greatly accelerated rate.
PRP Therapy in Orthopaedics and Sports Medicine
PRP is thought to promote physiological wound healing and rapid tissue regeneration by delivering growth factors at high concentrations to the treated site2.
How does Tropocells® PRP work?
The entire preparation process is simple and only takes up to 15 minutes.
PRP is prepared by having a small sample of the patient's own blood, then separating from RBCs, granulocytes and platelet poor plasma (PPP) via centrifugation. Once collected, PRP can be injected into the treated site to promote a healing response.
In the presence of granulocytes, platelets will release catabolic cytokines which inhibit the healing process. Therefore PRP rich in monocytes and low in neutrophils creates an ideal micro-environment for healing and growth. Tropocells® PRP has a high ratio of monocytes to neutrophils, 2.7:1.
What are the benefits of Tropocells® PRP?
Introducing a high concentration of platelets comprising bioactive proteins directly in the injured area may help in:
- Connective tissue healing and reducing scar tissue
- Bone regeneration (spinal fusion, bone fracture healing)
- Tendonitis/Tendonosis healing
- Cartilage and ligament regeneration and repair
- Development of new blood vessels
- Wound healing
Results may take between 2-6 weeks and will vary between individuals. This variance depends on factors such as general health, age, diet, smoking and skin type3.
Unique features of Tropocells® PRP
- 10 minute spin time
- Physiologic pH anti-coagulant
- Higher anabolic to catabolic cells ratio 22:1
- Monocytes outnumber neutrophils 2.7:1
- Maintains separations, eliminating RBCs from the concentration
- Option to use 11 mL tubes or 22 mL tubes
- Flexibility to concentrate PRP further
Are there any side effects?
The autologous nature of PRP reduces the likelihood of adverse reactions and possible side effects, which may be in a form of pain, swelling or infection. Standard skin disinfection should be used before PRP injection.
Contraindications include pregnancy, breast feeding, autoimmune or blood pathologies and cancer. Furthermore, consistent use of NSAIDs within 48 hours of PRP application should be avoided4.